# OnCo record h3-3a (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/h3-3a/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "h3-3a" ;
  schema:name "Histone H3.3 (H3-3A)"@en ;
  schema:alternateName "H3F3A"@en, "H3.3 histone A"@en, "histone H3.3"@en, "H3-3A" ;
  schema:description "H3.3 is one of the histone proteins DNA wraps around; a single change at position 27 (K27M) locks brain-stem and midline gliomas in an immature state and defines the diagnosis."@en ;
  schema:url <https://onco.cc/targets/h3-3a/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/H3F3A>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:4764>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000163041>, <https://www.uniprot.org/uniprotkb/P84243/entry>, <https://www.ncbi.nlm.nih.gov/gene/3020> ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:4764>, <https://www.uniprot.org/uniprotkb/P84243/entry> ;
  onco:tag "biomarker-parent" ;
  onco:targetClass "other" ;
  onco:related <https://onco.cc/biomarkers/h3-k27m/> ;
  onco:cancers <https://onco.cc/cancers/dipg-dmg/>, <https://onco.cc/cancers/paediatric-high-grade-glioma/> ;
  onco:drugs <https://onco.cc/drugs/dordaviprone/> ;
  onco:terms <https://onco.cc/terms/h3k27m/> .