# OnCo record hand-foot-syndrome (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/hand-foot-syndrome/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "hand-foot-syndrome" ;
  schema:name "Hand-foot syndrome and hand-foot skin reaction"@en ;
  schema:alternateName "hand-foot"@en, "hand-foot syndrome"@en, "hand foot syndrome"@en, "hand-foot skin reaction"@en, "HFSR"@en, "HFS"@en, "palmar-plantar erythrodysesthesia"@en, "PPE"@en, "palmar-plantar"@en, "plantar-palmar"@en ;
  schema:description "Redness, peeling, pain and cracking of the palms and soles caused by certain chemotherapy pills and by kinase inhibitors that block blood vessel growth. Rarely dangerous but can stop patients walking or using their hands."@en ;
  schema:url <https://onco.cc/terms/hand-foot-syndrome/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Chemotherapy-induced_acral_erythema> ;
  schema:citation <https://en.wikipedia.org/wiki/Chemotherapy-induced_acral_erythema>, <https://doi.org/10.1056/NEJMoa1612645>, <https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/folfirinox>, <https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/gemcap>, <https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/capecitabine>, <https://www.bowelcanceruk.org.uk/about-bowel-cancer/living-with-and-beyond-bowel-cancer/long-term-and-late-side-effects/> ;
  onco:related <https://onco.cc/terms/rash-skin-toxicity/>, <https://onco.cc/terms/dose-modification/>, <https://onco.cc/terms/tki-term/> ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/colorectal/> ;
  onco:sections <https://onco.cc/fronts/supportive-care/> ;
  onco:drugs <https://onco.cc/drugs/sorafenib/>, <https://onco.cc/drugs/regorafenib/>, <https://onco.cc/drugs/cabozantinib/>, <https://onco.cc/drugs/lenvatinib/> .