# OnCo record hck (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/hck/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "hck" ;
  schema:name "HCK kinase"@en ;
  schema:description "HCK is a SRC-family kinase of white blood cells that dasatinib and bosutinib inhibit; it drives growth in some leukaemias and in Waldenstrom macroglobulinaemia, where ibrutinib also hits it."@en ;
  schema:url <https://onco.cc/targets/hck/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/HCK>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:4840>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000101336>, <https://www.uniprot.org/uniprotkb/P08631/entry>, <https://www.ncbi.nlm.nih.gov/gene/3055> ;
  schema:citation <https://www.uniprot.org/uniprotkb/P08631/entry>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:4840>, <https://www.ebi.ac.uk/chembl/explore/target/CHEMBL3234> ;
  onco:tag "chembl-gap" ;
  schema:alternateName "HCK" ;
  onco:targetClass "kinase" ;
  onco:firstDescribed "1987"^^xsd:gYear ;
  onco:related <https://onco.cc/targets/lyn/>, <https://onco.cc/targets/btk/>, <https://onco.cc/targets/src/> ;
  onco:cancers <https://onco.cc/cancers/cml/>, <https://onco.cc/cancers/waldenstrom/>, <https://onco.cc/cancers/colorectal/> ;
  onco:drugs <https://onco.cc/drugs/dasatinib/>, <https://onco.cc/drugs/bosutinib/>, <https://onco.cc/drugs/ibrutinib/> .