# OnCo record hedgehog (pathway). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pathways/hedgehog/>
  a schema:BioChemEntity ;
  onco:kind "pathway" ;
  schema:identifier "hedgehog" ;
  schema:name "Hedgehog signalling"@en ;
  schema:description "A developmental pathway that shapes embryos and is switched back on in basal cell skin cancer and some brain tumours. Blocking it cures most advanced basal cell carcinomas, but tumours learn to reactivate it downstream."@en ;
  schema:url <https://onco.cc/pathways/hedgehog/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Hedgehog_signaling_pathway> ;
  owl:sameAs <http://www.wikidata.org/entity/Q14859918> ;
  schema:citation <https://doi.org/10.1056/NEJMoa1113713> ;
  onco:tag "mechanism" ;
  onco:cancers <https://onco.cc/cancers/glioblastoma/>, <https://onco.cc/cancers/aml/> ;
  onco:technologies <https://onco.cc/technologies/kinase-inhibitors/>, <https://onco.cc/technologies/hedgehog-inhibitors/> ;
  onco:targets <https://onco.cc/targets/ptch1/> ;
  onco:institutions <https://onco.cc/institutions/stanford/>, <https://onco.cc/institutions/dana-farber/> ;
  onco:pathways <https://onco.cc/pathways/wnt/>, <https://onco.cc/pathways/notch/>, <https://onco.cc/pathways/cancer-stem-cells-plasticity/> .