# OnCo record hepatosplenic-t-cell-lymphoma (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/hepatosplenic-t-cell-lymphoma/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "hepatosplenic-t-cell-lymphoma" ;
  schema:name "Hepatosplenic T-cell lymphoma"@en ;
  schema:alternateName "HSTCL"@en, "HSTL"@en, "Hepatosplenic gamma-delta T-cell lymphoma"@en, "Enteropathy-associated and hepatosplenic T-cell lymphoma"@en ;
  schema:description "Hepatosplenic T-cell lymphoma is a rare, very aggressive lymphoma of young men in which gamma-delta T cells fill the liver, spleen and bone marrow without forming lumps in the nodes. It is linked to long-term immune suppression, above all thiopurines with or without anti-TNF drugs for inflammatory bowel disease, and is treated with intensive chemotherapy then a stem cell transplant where possible."@en ;
  schema:url <https://onco.cc/cancers/hepatosplenic-t-cell-lymphoma/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Hepatosplenic_T-cell_lymphoma> ;
  schema:citation <https://www.cancer.gov/types/lymphoma/patient/adult-nhl-treatment-pdq>, <https://doi.org/10.1038/s41375-022-01620-2>, <https://doi.org/10.1158/2159-8290.cd-16-0330>, <https://doi.org/10.1016/j.cgh.2010.09.016> ;
  onco:tag "subtype-page", "wave4", "haematologic", "rare" ;
  onco:related <https://onco.cc/cancers/peripheral-t-cell-lymphoma/>, <https://onco.cc/cancers/angioimmunoblastic-t-cell-lymphoma/>, <https://onco.cc/cancers/t-large-granular-lymphocytic-leukaemia/>, <https://onco.cc/cancers/post-transplant-lymphoproliferative-disorder/> ;
  onco:targets <https://onco.cc/targets/stat3/> ;
  onco:drugs <https://onco.cc/drugs/cytarabine/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/etoposide/> ;
  onco:pathways <https://onco.cc/pathways/jak-stat/> ;
  onco:terms <https://onco.cc/terms/allogeneic-transplant/> ;
  onco:standardOfCare <https://onco.cc/cancers/peripheral-t-cell-lymphoma/>, <https://onco.cc/drugs/cytarabine/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/terms/allogeneic-transplant/> .