# OnCo record hepatotoxicity (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/hepatotoxicity/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "hepatotoxicity" ;
  schema:name "Hepatotoxicity (liver enzyme elevation)"@en ;
  schema:alternateName "liver toxicity"@en, "hepatic toxicity"@en, "hepatotoxic"@en, "transaminitis"@en, "transaminase elevation"@en, "elevated transaminases"@en, "raised liver enzymes"@en, "liver enzymes"@en, "ALT/AST"@en, "liver function tests"@en, "LFTs"@en, "drug-induced liver injury"@en, "DILI"@en, "immune hepatitis"@en, "immune-mediated hepatitis"@en, "hepatitis B reactivation"@en, "HBV reactivation"@en, "veno-occlusive disease"@en, "sinusoidal obstruction syndrome"@en, "VOD/SOS"@en, "hyperbilirubinaemia"@en, "liver enzyme"@en ;
  schema:description "Liver injury from a drug, usually detected as a rise in liver enzymes (ALT, AST) on routine blood tests before symptoms appear. Most cases settle with a pause or dose reduction; a few, especially with checkpoint inhibitors or in already damaged livers, are serious."@en ;
  schema:url <https://onco.cc/terms/hepatotoxicity/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Hepatotoxicity> ;
  schema:citation <https://en.wikipedia.org/wiki/Hepatotoxicity> ;
  onco:related <https://onco.cc/terms/cirrhosis/>, <https://onco.cc/terms/irae/>, <https://onco.cc/terms/dose-modification/>, <https://onco.cc/terms/child-pugh/> ;
  onco:sections <https://onco.cc/fronts/supportive-care/> .