# OnCo record her2-testing-uk-breast (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/her2-testing-uk-breast/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "her2-testing-uk-breast" ;
  schema:name "HER2 testing in the UK: reflex ISH, the ratio against the copy number, and where the UK differs from ASCO/CAP"@en ;
  schema:alternateName "HER2 testing"@en, "HER2 test"@en, "HER2 IHC 2+"@en, "reflex ISH"@en, "dual-probe ISH"@en, "HER2 CEP17 ratio"@en, "HER2 copy number"@en, "FISH group 2"@en, "HER2 equivocal"@en, "HER2 borderline"@en, "HER2 heterogeneity"@en, "UK HER2 recommendations"@en, "chicken wire"@en ;
  schema:description "HER2 is scored 0 to 3+ on the stain; 3+ is positive, 0 and 1+ are negative, and 2+ goes on for a gene test. The UK reads one borderline gene result as positive where the American guideline reads it as negative, so the same tumour can be HER2-positive in Britain and HER2-negative in the United States."@en ;
  schema:url <https://onco.cc/terms/her2-testing-uk-breast/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://www.rcpath.org/resourceLibrary/g148-dataset-for-histopathological-reporting-of-breast-disease-in-surgical-excision-specimens-of-breast-cancer.html>, <https://doi.org/10.1136/jcp-2022-208632>, <https://doi.org/10.1111/his.70149> ;
  onco:related <https://onco.cc/terms/her2-positive/>, <https://onco.cc/terms/her2-low/>, <https://onco.cc/terms/fish/>, <https://onco.cc/terms/ihc/>, <https://onco.cc/terms/co-amplification/> ;
  onco:cancers <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/breast-her2-positive/>, <https://onco.cc/cancers/her2-low-metastatic-breast-cancer/>, <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/breast-hr-positive/> ;
  onco:sections <https://onco.cc/fronts/diagnostics/>, <https://onco.cc/fronts/targeted-therapy/> ;
  onco:terms <https://onco.cc/terms/her2-positive/>, <https://onco.cc/terms/her2-low/>, <https://onco.cc/terms/her2-low-and-trop2-adc-eligibility-tnbc/>, <https://onco.cc/terms/er-pr-scoring-breast/>, <https://onco.cc/terms/receptor-conversion-breast/>, <https://onco.cc/terms/grade-stage-receptor-breast/>, <https://onco.cc/terms/fish/>, <https://onco.cc/terms/ihc/> .