# OnCo record her3 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/her3/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "her3" ;
  schema:name "HER3"@en ;
  schema:description "HER3 is a cousin of HER2 that cancers use as an escape route when HER2 or EGFR are blocked."@en ;
  schema:url <https://onco.cc/targets/her3/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/ERBB3>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3431>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000065361>, <https://www.uniprot.org/uniprotkb/P21860/entry>, <https://www.ncbi.nlm.nih.gov/gene/2065> ;
  owl:sameAs <http://www.wikidata.org/entity/Q17917132> ;
  schema:citation <https://en.wikipedia.org/wiki/ERBB3> ;
  onco:tag "adc-target", "resistance" ;
  schema:alternateName "ERBB3" ;
  onco:targetClass "surface-antigen" ;
  onco:firstDescribed "1989"^^xsd:gYear ;
  onco:related <https://onco.cc/biomarkers/nrg1-fusion/>, <https://onco.cc/biomarkers/her3-expression/> ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/gallbladder/> ;
  onco:drugs <https://onco.cc/drugs/yl202/>, <https://onco.cc/drugs/hmbd-001/>, <https://onco.cc/drugs/env-501/>, <https://onco.cc/drugs/sys6023/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-li-gallbladder-exome-erbb-nat-genet-2014/>, <https://onco.cc/key-papers/paper-narayan-gallbladder-regional-mutations-cancer-2019/> .