# OnCo record hereditary-diffuse-gastric-cancer (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/hereditary-diffuse-gastric-cancer/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "hereditary-diffuse-gastric-cancer" ;
  schema:name "Hereditary diffuse gastric cancer"@en ;
  schema:alternateName "HDGC"@en, "hereditary diffuse gastric cancer syndrome"@en ;
  schema:description "Hereditary diffuse gastric cancer is an inherited condition, usually caused by a fault in the CDH1 gene, that carries a high risk of a type of stomach cancer that spreads through the stomach wall and of lobular breast cancer. Removing the whole stomach before cancer develops is the recommended option, and expert endoscopy checks can be offered to people who want to delay surgery."@en ;
  schema:url <https://onco.cc/terms/hereditary-diffuse-gastric-cancer/> ;
  schema:dateModified "2026-11-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Hereditary_diffuse_gastric_cancer> ;
  schema:citation <https://doi.org/10.1016/S1470-2045(20)30219-9>, <https://www.orpha.net/en/disease/detail/26106>, <https://www.england.nhs.uk/wp-content/uploads/2018/08/rare-and-inherited-disease-national-genomics-test-directory-v9.xlsx> ;
  onco:tag "gap-fill", "hereditary" ;
  onco:cancers <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/invasive-lobular-carcinoma/> ;
  onco:technologies <https://onco.cc/technologies/germline-testing/> ;
  onco:targets <https://onco.cc/targets/cdh1/>, <https://onco.cc/targets/ctnna1/> ;
  onco:terms <https://onco.cc/terms/gastrectomy/>, <https://onco.cc/terms/endoscopy/>, <https://onco.cc/terms/hereditary-cancer-syndromes/> .