# OnCo record hla-e (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/hla-e/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "hla-e" ;
  schema:name "HLA-E"@en ;
  schema:alternateName "major histocompatibility complex, class I, E"@en, "HLA class I histocompatibility antigen, alpha chain E"@en, "HLA-E" ;
  schema:description "HLA-E is the self badge that NKG2A on NK cells reads. Tumours raise it to escape NK cells; monalizumab blocks the reader rather than the badge."@en ;
  schema:url <https://onco.cc/targets/hla-e/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:4962>, <https://www.uniprot.org/uniprotkb/P13747/entry>, <https://www.ncbi.nlm.nih.gov/gene/3133> ;
  onco:tag "checkpoint-map" ;
  onco:targetClass "checkpoint" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:4962>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000204592>, <https://www.uniprot.org/uniprotkb/P13747/entry>, <https://www.ncbi.nlm.nih.gov/gene/3133> ;
  onco:related <https://onco.cc/targets/klrc1/>, <https://onco.cc/drugs/monalizumab/>, <https://onco.cc/targets/hla-a/> ;
  onco:pathways <https://onco.cc/pathways/cancer-immunity-cycle/> .