# OnCo record hmb-supplements (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/hmb-supplements/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "hmb-supplements" ;
  schema:name "HMB (beta-hydroxy-beta-methylbutyrate)"@en ;
  schema:alternateName "HMB"@en, "Beta-hydroxy-beta-methylbutyrate"@en, "HMB, arginine and glutamine"@en ;
  schema:description "HMB, a breakdown product of the amino acid leucine, is sold to preserve muscle and is added to some medical drinks for cancer weight loss, often with arginine and glutamine. A larger randomised trial of that combination in cancer wasting found no significant effect, and analyses show at most small gains in muscle across other illnesses."@en ;
  schema:url <https://onco.cc/technologies/hmb-supplements/> ;
  schema:dateModified "2026-11-04"^^xsd:date ;
  schema:citation <https://www.mskcc.org/cancer-care/integrative-medicine/herbs/hmb> ;
  onco:status "negative" ;
  onco:tag "complementary", "supportive-care", "evidence:no-benefit" ;
  onco:related <https://onco.cc/technologies/creatine-supplements/>, <https://onco.cc/technologies/carnitine-acetyl-l-carnitine/> ;
  onco:sections <https://onco.cc/fronts/supportive-care/>, <https://onco.cc/fronts/nutrition-lifestyle/> ;
  onco:technologies <https://onco.cc/technologies/integrative-oncology/>, <https://onco.cc/technologies/dietary-supplements-treatment-interactions/>, <https://onco.cc/technologies/resistance-training-cachexia/>, <https://onco.cc/technologies/cachexia-appetite-pharmacotherapy/>, <https://onco.cc/technologies/glutamine-mucositis-neuropathy/> ;
  onco:drugs <https://onco.cc/drugs/everolimus/>, <https://onco.cc/drugs/sirolimus/> ;
  onco:terms <https://onco.cc/terms/cachexia/>, <https://onco.cc/terms/sarcopenia/>, <https://onco.cc/terms/radiation-dermatitis/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-toxicity-qol/> .