# OnCo record hpv-associated-vulvar-cancer (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/hpv-associated-vulvar-cancer/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "hpv-associated-vulvar-cancer" ;
  schema:name "HPV-associated vulvar squamous cell carcinoma"@en ;
  schema:alternateName "HPV-positive vulvar cancer"@en, "p16-positive vulvar squamous cell carcinoma"@en, "Basaloid and warty vulvar carcinoma"@en, "Vulvar cancer arising from usual-type VIN"@en ;
  schema:description "HPV-associated vulvar cancer is the type of vulvar squamous cell cancer caused by persistent HPV infection, growing out of the precancer called usual-type VIN and marked by the p16 protein. It tends to affect younger women, responds better to radiotherapy and recurs less often than the HPV-independent type, and it is preventable by HPV vaccination."@en ;
  schema:url <https://onco.cc/cancers/hpv-associated-vulvar-cancer/> ;
  schema:dateModified "2026-09-18"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Vulvar_cancer> ;
  schema:citation <https://doi.org/10.1200/JCO.21.00006>, <https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1476>, <https://en.wikipedia.org/wiki/Vulvar_cancer> ;
  onco:tag "subtype-page", "gynaecologic" ;
  onco:related <https://onco.cc/cancers/hpv-independent-vulvar-cancer/>, <https://onco.cc/cancers/vulvar/>, <https://onco.cc/cancers/vaginal-squamous-cell-carcinoma/> ;
  onco:technologies <https://onco.cc/technologies/sentinel-node/>, <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/technologies/hpv-vaccine/>, <https://onco.cc/technologies/precancer-ablation/> ;
  onco:targets <https://onco.cc/targets/pd1/> ;
  onco:drugs <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/drugs/bevacizumab/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/gardasil-9/> ;
  onco:terms <https://onco.cc/terms/hpv-p16/>, <https://onco.cc/terms/cps/>, <https://onco.cc/terms/lymphadenectomy/>, <https://onco.cc/terms/chemoradiation/> ;
  onco:trials <https://onco.cc/trials/nct06075264/>, <https://onco.cc/trials/nct04422366/>, <https://onco.cc/trials/nct05903833/>, <https://onco.cc/trials/nct05932212/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-groinss-v-sentinel-node-vulvar-cancer-jco-2008/>, <https://onco.cc/key-papers/paper-groinss-v-ii-radiotherapy-vulvar-micrometastases-jco-2021/> ;
  onco:pipeline <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/trials/nct05903833/>, <https://onco.cc/trials/nct05932212/>, <https://onco.cc/trials/nct06075264/>, <https://onco.cc/technologies/hpv-vaccine/> ;
  onco:standardOfCare <https://onco.cc/technologies/precancer-ablation/>, <https://onco.cc/technologies/hpv-vaccine/>, <https://onco.cc/drugs/gardasil-9/>, <https://onco.cc/trials/nct06075264/>, <https://onco.cc/trials/nct04422366/>, <https://onco.cc/technologies/sentinel-node/>, <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/terms/lymphadenectomy/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/terms/chemoradiation/>, <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/drugs/bevacizumab/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/trials/nct05903833/>, <https://onco.cc/trials/nct05932212/> .