# OnCo record hpv-quadrivalent-vaccine (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/hpv-quadrivalent-vaccine/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "hpv-quadrivalent-vaccine" ;
  schema:name "HPV quadrivalent vaccine (types 6, 11, 16 and 18)"@en ;
  schema:alternateName "Silgard"@en, "Gardasil" ;
  schema:description "Gardasil was the first HPV vaccine, licensed in 2006 to prevent cervical and other genital cancers and genital warts. It has been replaced in most countries by the nine-type version, Gardasil 9."@en ;
  schema:url <https://onco.cc/drugs/hpv-quadrivalent-vaccine/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Gardasil> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=Gardasil>, <https://www.cancer.gov/about-cancer/treatment/drugs/recombinant-hpv-quadrivalent-vaccine>, <https://www.ema.europa.eu/en/medicines/human/EPAR/gardasil> ;
  onco:status "approved" ;
  onco:tag "nci-list", "prevention" ;
  onco:modality "Recombinant virus-like particle vaccine" ;
  onco:approval "US 2006: Prevention of cervical, vulvar and vaginal cancers and precancers and genital warts caused by HPV 6, 11, 16 and 18 in females 9 to 26 (males 2009; anal cancer 2010); superseded by Gardasil 9", "EU 2006: Prevention of premalignant genital lesions, cervical cancer and genital warts from age 9 (Gardasil); anal lesions and cancer added later" ;
  onco:related <https://onco.cc/drugs/gardasil-9/>, <https://onco.cc/drugs/hpv-bivalent-vaccine/> ;
  onco:cancers <https://onco.cc/cancers/cervical/>, <https://onco.cc/cancers/vulvar/>, <https://onco.cc/cancers/anal/> ;
  onco:technologies <https://onco.cc/technologies/hpv-vaccine/>, <https://onco.cc/technologies/interception-vaccination/> ;
  onco:companies <https://onco.cc/companies/merck/> ;
  onco:trials <https://onco.cc/trials/nct04422366/>, <https://onco.cc/trials/nct06465914/> .