# OnCo record hrd (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/hrd/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "hrd" ;
  schema:name "Homologous recombination deficiency (HRD)"@en ;
  schema:description "A tumour that cannot properly repair double-strand DNA breaks, usually because of BRCA or related gene loss."@en ;
  schema:url <https://onco.cc/terms/hrd/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Homologous_recombination> ;
  owl:sameAs <http://www.wikidata.org/entity/Q22280388> ;
  schema:citation <https://en.wikipedia.org/wiki/Homologous_recombination> ;
  onco:related <https://onco.cc/terms/genome-wide-loss-of-heterozygosity/> ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mcrpc/> ;
  onco:technologies <https://onco.cc/technologies/hrd-testing/> ;
  onco:targets <https://onco.cc/targets/brca/>, <https://onco.cc/targets/parp/> ;
  onco:terms <https://onco.cc/terms/genome-wide-loss-of-heterozygosity/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-pritchard-inherited-dna-repair-metastatic-prostate-nejm-2016/>, <https://onco.cc/key-papers/paper-robinson-integrative-clinical-genomics-advanced-prostate-cell-2015/> .