# OnCo record htr3a (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/htr3a/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "htr3a" ;
  schema:name "5-HT3 receptor (HTR3A)"@en ;
  schema:description "The serotonin receptor on the gut's vagus nerve endings and in the brainstem vomiting centre that chemotherapy triggers. Ondansetron and palonosetron block it, the foundation of modern anti-sickness treatment."@en ;
  schema:url <https://onco.cc/targets/htr3a/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/5-HT3_receptor>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:5297>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000166736>, <https://www.uniprot.org/uniprotkb/P46098/entry>, <https://www.ncbi.nlm.nih.gov/gene/3359> ;
  schema:citation <https://www.uniprot.org/uniprotkb/P46098/entry> ;
  schema:alternateName "HTR3A" ;
  onco:targetClass "other" ;
  onco:firstDescribed "1995"^^xsd:gYear ;
  onco:related <https://onco.cc/targets/tacr1/> ;
  onco:drugs <https://onco.cc/drugs/ondansetron/>, <https://onco.cc/drugs/palonosetron/>, <https://onco.cc/drugs/granisetron/>, <https://onco.cc/drugs/dolasetron/> .