# OnCo record hydroxyurea (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/hydroxyurea/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "hydroxyurea" ;
  schema:name "Hydroxyurea (hydroxycarbamide)"@en ;
  schema:description "Hydroxyurea is a cheap, decades-old pill that lowers high blood counts in polycythaemia vera and essential thrombocythaemia and is also the main drug for sickle cell disease."@en ;
  schema:url <https://onco.cc/drugs/hydroxyurea/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Hydroxycarbamide> ;
  owl:sameAs <http://www.wikidata.org/entity/Q212272> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=hydroxyurea> ;
  onco:status "approved" ;
  onco:tag "gap-fill", "generic" ;
  onco:modality "Oral ribonucleotide reductase inhibitor (cytoreductive)" ;
  schema:alternateName "Hydrea / Droxia / Siklos" ;
  onco:approval "US 1967: CML, head and neck cancer with radiotherapy, melanoma, ovarian cancer (historic labelling)", "US 1998: Sickle cell anaemia (Droxia)" ;
  onco:cancers <https://onco.cc/cancers/myeloproliferative-neoplasms/>, <https://onco.cc/cancers/cml/>, <https://onco.cc/cancers/polycythaemia-vera/>, <https://onco.cc/cancers/essential-thrombocythaemia/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:companies <https://onco.cc/companies/bms/> .