# OnCo record hyperleukocytosis-leukostasis (protocol). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/protocols/hyperleukocytosis-leukostasis/>
  a schema:MedicalGuideline ;
  onco:kind "protocol" ;
  schema:identifier "hyperleukocytosis-leukostasis" ;
  schema:name "Hyperleukocytosis and leukostasis in acute leukaemia: supportive care, cytoreduction and leukapheresis"@en ;
  schema:alternateName "leukostasis"@en, "hyperleukocytosis"@en, "white cell count over 100"@en, "leukapheresis for AML"@en, "leukoreduction"@en ;
  schema:description "In some leukaemias the white cell count is so high that the blood thickens and blocks small vessels in the lungs, brain and kidneys. This leukostasis is an emergency. The cells are brought down quickly with hydroxyurea and then chemotherapy; sometimes a machine filters them out. Blood transfusions are avoided unless really needed, because they thicken the blood further."@en ;
  schema:url <https://onco.cc/protocols/hyperleukocytosis-leukostasis/> ;
  schema:dateModified "2026-11-11"^^xsd:date ;
  onco:tag "protocol", "acute-oncology", "oncological-emergency", "haematology" ;
  onco:related <https://onco.cc/protocols/tumour-lysis-syndrome-prevention-and-treatment/> ;
  onco:cancers <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/leukaemia/> ;
  onco:drugs <https://onco.cc/drugs/hydroxyurea/>, <https://onco.cc/drugs/tretinoin-atra/>, <https://onco.cc/drugs/allopurinol/>, <https://onco.cc/drugs/rasburicase/>, <https://onco.cc/drugs/cytarabine/> ;
  onco:terms <https://onco.cc/terms/apheresis/>, <https://onco.cc/terms/tumor-lysis-syndrome/> .