# OnCo record ibis-ii (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/ibis-ii/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "ibis-ii", "ISRCTN31488319" ;
  schema:name "IBIS-II (International Breast Intervention Study II)"@en ;
  schema:alternateName "IBIS-2"@en, "IBIS-II Prevention"@en, "ISRCTN31488319"@en ;
  schema:description "The trial that made anastrozole a prevention drug, halving breast cancer in postmenopausal women at high risk and, with a licence granted in 2023, putting a generic tablet on the NHS prevention pathway."@en ;
  schema:url <https://onco.cc/trials/ibis-ii/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/S0140-6736(19)32955-1>, <https://www.isrctn.com/ISRCTN31488319>, <https://www.nice.org.uk/guidance/cg164/chapter/Recommendations> ;
  onco:status "positive" ;
  onco:tag "uk", "breast", "prevention" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/breast-cancer/> ;
  onco:drugs <https://onco.cc/drugs/anastrozole/>, <https://onco.cc/drugs/tamoxifen/> ;
  onco:people <https://onco.cc/people/jack-cuzick/> .