# OnCo record icans-grading-and-management (protocol). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: .
@prefix onco: .
@prefix xsd: .
a schema:MedicalGuideline ;
onco:kind "protocol" ;
schema:identifier "icans-grading-and-management" ;
schema:name "ICANS after CAR T-cell therapy: ICE score, ASTCT grading, steroids and seizure management"@en ;
schema:alternateName "ICANS management"@en, "immune effector cell-associated neurotoxicity syndrome"@en, "ICE score"@en, "CAR-T neurotoxicity"@en, "CAPD score for children"@en ;
schema:description "In the weeks after CAR T-cell therapy, some people become confused, struggle to find words or write, become very sleepy, or rarely have seizures. This is ICANS. Nurses check a short test of orientation, naming, writing and counting (the ICE score). Steroids such as dexamethasone treat it, and most people recover. A carer who notices confusion or odd speech should call the centre at once."@en ;
schema:url ;
schema:dateModified "2026-11-11"^^xsd:date ;
onco:tag "protocol", "cell-therapy", "car-t", "acute-oncology" ;
onco:related ;
onco:technologies ;
onco:drugs , , , , , , , , ;
onco:institutions ;
onco:terms , .