# OnCo record icotinib (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/icotinib/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "icotinib" ;
  schema:name "Icotinib"@en ;
  schema:description "Icotinib, approved in 2011, was the first cancer drug invented and developed in China, and it showed that a domestic lung cancer pill could match a Western one head to head."@en ;
  schema:url <https://onco.cc/drugs/icotinib/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Icotinib> ;
  schema:citation <https://www.bettapharma.com/>, <https://doi.org/10.1016/S1470-2045(13)70355-3>, <https://www.nmpa.gov.cn> ;
  onco:status "approved" ;
  onco:tag "china" ;
  onco:modality "Small-molecule first-generation EGFR TKI" ;
  schema:alternateName "Conmana" ;
  onco:approval "China 2011: Advanced NSCLC after failure of at least one chemotherapy regimen (ICOGEN)", "China 2014: First-line EGFR-mutant NSCLC", "China 2021: Adjuvant treatment of resected stage II to IIIA EGFR-mutant NSCLC (EVIDENCE)" ;
  onco:cancers <https://onco.cc/cancers/nsclc/> ;
  onco:technologies <https://onco.cc/technologies/kinase-inhibitors/> ;
  onco:targets <https://onco.cc/targets/egfr/> ;
  onco:companies <https://onco.cc/companies/betta/> ;
  onco:pathways <https://onco.cc/pathways/ras-mapk/> ;
  onco:trials <https://onco.cc/trials/nct06041776/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-shi-lancet-oncol/> .