# OnCo record idea-alpha-after-adc (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-alpha-after-adc/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-alpha-after-adc" ;
  schema:name "Alpha radioligands after ADC failure"@en ;
  schema:description "When ADCs against a surface protein stop working because the payload no longer kills, use the same protein to deliver radiation instead."@en ;
  schema:url <https://onco.cc/ideas/idea-alpha-after-adc/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  onco:related <https://onco.cc/ideas/idea-payload-switching/> ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/breast-hr-positive/> ;
  onco:technologies <https://onco.cc/technologies/radioimmunotherapy/>, <https://onco.cc/technologies/targeted-alpha-therapy/>, <https://onco.cc/technologies/adc/>, <https://onco.cc/technologies/trop2-pet/> ;
  onco:targets <https://onco.cc/targets/trop2/>, <https://onco.cc/targets/her2/>, <https://onco.cc/targets/b7h3/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-yarden-sliwkowski-erbb-network-nrmcb-2001/> .