# OnCo record idea-atc-triplet-io (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-atc-triplet-io/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-atc-triplet-io" ;
  schema:name "BRAF/MEK plus PD-1 blockade as standard for BRAF-mutant anaplastic thyroid cancer"@en ;
  schema:description "Add immunotherapy to the two targeted pills in the most aggressive thyroid cancer, because the combination has produced multi-year survivors in early series."@en ;
  schema:url <https://onco.cc/ideas/idea-atc-triplet-io/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02034110> ;
  onco:cancers <https://onco.cc/cancers/thyroid/> ;
  onco:targets <https://onco.cc/targets/braf/>, <https://onco.cc/targets/pd1/> ;
  onco:drugs <https://onco.cc/drugs/dabrafenib-trametinib/>, <https://onco.cc/drugs/pembrolizumab/> ;
  onco:trials <https://onco.cc/trials/roar-atc/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-braf-thyroid-n-engl-j-med-2015/>, <https://onco.cc/key-papers/paper-braf-thyroid-endocr-relat-cancer-2005/>, <https://onco.cc/key-papers/paper-braf-thyroid-endocr-rev-2007/> .