# OnCo record idea-bio1-alternating-schedules (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-bio1-alternating-schedules/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-bio1-alternating-schedules" ;
  schema:name "Rotate between drugs on a fixed schedule instead of waiting for failure"@en ;
  schema:description "Hospitals rotate antibiotics to stop bacteria adapting. Cycling between two cancer drugs on a set schedule, rather than using one until it fails, might work the same way."@en ;
  schema:url <https://onco.cc/ideas/idea-bio1-alternating-schedules/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa1713137> ;
  onco:related <https://onco.cc/roadmaps/prostate-roadmap/>, <https://onco.cc/ideas/idea-prostate-bipolar-androgen-therapy-phase-3-on-pfs2/>, <https://onco.cc/ideas/idea-prostate-randomise-the-sequence-not-only-the-drugs/> ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/prostate/> ;
  onco:technologies <https://onco.cc/technologies/endocrine-therapy/> ;
  onco:terms <https://onco.cc/terms/bipolar-androgen-therapy/>, <https://onco.cc/terms/intermittent-androgen-deprivation/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-resistance/>, <https://onco.cc/bottlenecks/b-combination-space/> .