# OnCo record idea-bio1-co-clinical-avatar-trials (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-bio1-co-clinical-avatar-trials/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-bio1-co-clinical-avatar-trials" ;
  schema:name "Run the mouse or organoid trial at the same time as the human trial"@en ;
  schema:description "Instead of testing a drug in lab models first and hoping the results carry over, build the same models from trial participants and run both experiments in parallel to see how well the models predict."@en ;
  schema:url <https://onco.cc/ideas/idea-bio1-co-clinical-avatar-trials/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1093/biostatistics/kxx069> ;
  onco:related <https://onco.cc/ideas/idea-organoid-guided-adc/> ;
  onco:technologies <https://onco.cc/technologies/organoids/>, <https://onco.cc/technologies/pdx-models/>, <https://onco.cc/technologies/functional-drug-testing/> ;
  onco:companies <https://onco.cc/companies/champions-oncology/>, <https://onco.cc/companies/xilis/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-preclinical-models/>, <https://onco.cc/bottlenecks/b-biomarker-validation/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-wong-biostatistics/> .