# OnCo record idea-bio1-collateral-sensitivity-atlas (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-bio1-collateral-sensitivity-atlas/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-bio1-collateral-sensitivity-atlas" ;
  schema:name "An open atlas of collateral sensitivity for every approved targeted drug"@en ;
  schema:description "When a tumour evolves resistance to one drug, it sometimes becomes weaker against another. Map these trade-offs systematically so doctors can pick the next drug to exploit them."@en ;
  schema:url <https://onco.cc/ideas/idea-bio1-collateral-sensitivity-atlas/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa1113205> ;
  onco:technologies <https://onco.cc/technologies/functional-drug-testing/>, <https://onco.cc/technologies/crispr-screens/> ;
  onco:institutions <https://onco.cc/institutions/broad-institute/> ;
  onco:terms <https://onco.cc/terms/resistance/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-tumor-heterogeneity/>, <https://onco.cc/bottlenecks/b-resistance/>, <https://onco.cc/bottlenecks/b-combination-space/> .