# OnCo record idea-bio1-epigenetic-persister-blockade (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-bio1-epigenetic-persister-blockade/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-bio1-epigenetic-persister-blockade" ;
  schema:name "Block the chemical switch that lets cells hide from treatment"@en ;
  schema:description "Cells that survive treatment do so by changing which genes they use, not their DNA. Drugs that block that change may stop survivors from forming at all."@en ;
  schema:url <https://onco.cc/ideas/idea-bio1-epigenetic-persister-blockade/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa1713137> ;
  onco:technologies <https://onco.cc/technologies/epigenetic-drugs/> ;
  onco:targets <https://onco.cc/targets/ezh2/> ;
  onco:terms <https://onco.cc/terms/resistance/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-resistance/> .