# OnCo record idea-bio1-immune-matched-humanised-mice (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-bio1-immune-matched-humanised-mice/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-bio1-immune-matched-humanised-mice" ;
  schema:name "Humanised mice with an immune system matched to the tumour donor"@en ;
  schema:description "Most cancer drugs are tested in mice with no immune system, then given to people who have one. Mice carrying the same patient's immune cells and tumour would be a fairer test."@en ;
  schema:url <https://onco.cc/ideas/idea-bio1-immune-matched-humanised-mice/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1093/biostatistics/kxx069> ;
  onco:technologies <https://onco.cc/technologies/pdx-models/>, <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:companies <https://onco.cc/companies/champions-oncology/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-preclinical-models/>, <https://onco.cc/bottlenecks/b-immunotherapy-response/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-wong-biostatistics/> .