# OnCo record idea-bio1-resistance-mutation-vaccine (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-bio1-resistance-mutation-vaccine/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-bio1-resistance-mutation-vaccine" ;
  schema:name "Vaccinate against the resistance mutation before it takes over"@en ;
  schema:description "Resistance often arrives as the same few mutations. Teaching the immune system to recognise them in advance could remove the escaping cells while they are still rare."@en ;
  schema:url <https://onco.cc/ideas/idea-bio1-resistance-mutation-vaccine/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa1713137> ;
  onco:technologies <https://onco.cc/technologies/shared-antigen-vaccine/>, <https://onco.cc/technologies/neoantigen-mrna-vaccine/> ;
  onco:targets <https://onco.cc/targets/egfr/>, <https://onco.cc/targets/estrogen-receptor/> ;
  onco:terms <https://onco.cc/terms/neoantigen/>, <https://onco.cc/terms/resistance/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-resistance/>, <https://onco.cc/bottlenecks/b-immunotherapy-response/> .