# OnCo record idea-bio2-autophagy-block-mrd (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-bio2-autophagy-block-mrd/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-bio2-autophagy-block-mrd" ;
  schema:name "Block the recycling that keeps dormant cells alive"@en ;
  schema:description "Sleeping cancer cells survive by recycling their own contents. An old malaria drug blocks that recycling and is being tested in people with no visible cancer but detectable residual cells."@en ;
  schema:url <https://onco.cc/ideas/idea-bio2-autophagy-block-mrd/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa2200075> ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/tnbc/> ;
  onco:technologies <https://onco.cc/technologies/mrd-testing/>, <https://onco.cc/technologies/liquid-biopsy/> ;
  onco:drugs <https://onco.cc/drugs/everolimus/> ;
  onco:institutions <https://onco.cc/institutions/johns-hopkins/> ;
  onco:terms <https://onco.cc/terms/mrd/>, <https://onco.cc/terms/late-recurrence/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-dormancy-mrd/>, <https://onco.cc/bottlenecks/b-generic-repurposing/> .