# OnCo record idea-bio2-blood-csf-barrier-model (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-bio2-blood-csf-barrier-model/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-bio2-blood-csf-barrier-model" ;
  schema:name "Build a human model of the barrier that guards the brain fluid"@en ;
  schema:description "Drugs that reach brain tissue may still fail to reach the fluid where cancer spreads along the linings. A lab model of that second barrier would let us screen for drugs that cross it."@en ;
  schema:url <https://onco.cc/ideas/idea-bio2-blood-csf-barrier-model/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa043330> ;
  onco:cancers <https://onco.cc/cancers/breast-her2-positive/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/melanoma/> ;
  onco:technologies <https://onco.cc/technologies/organoids/> ;
  onco:terms <https://onco.cc/terms/blood-brain-barrier/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-brain-delivery/>, <https://onco.cc/bottlenecks/b-preclinical-models/> .