# OnCo record idea-bio2-brain-met-prevention-trials (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-bio2-brain-met-prevention-trials/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-bio2-brain-met-prevention-trials" ;
  schema:name "Prevention trials aimed only at brain metastasis"@en ;
  schema:description "Some cancers reach the brain in up to a quarter of patients. Prevention trials could aim specifically at stopping that, instead of treating it once it has happened."@en ;
  schema:url <https://onco.cc/ideas/idea-bio2-brain-met-prevention-trials/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1002/cam4.2474> ;
  onco:related <https://onco.cc/roadmaps/lung-cancer-evidence-roadmap/>, <https://onco.cc/ideas/idea-lung-brain-metastasis-prevention-as-a-primary-endpoint/> ;
  onco:cancers <https://onco.cc/cancers/breast-her2-positive/>, <https://onco.cc/cancers/nsclc/> ;
  onco:technologies <https://onco.cc/technologies/mri/> ;
  onco:drugs <https://onco.cc/drugs/tucatinib/>, <https://onco.cc/drugs/osimertinib/>, <https://onco.cc/drugs/alectinib/>, <https://onco.cc/drugs/lorlatinib/> ;
  onco:terms <https://onco.cc/terms/her2-brain-metastases/> ;
  onco:trials <https://onco.cc/trials/alina/>, <https://onco.cc/trials/adaura/>, <https://onco.cc/trials/her2climb/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-metastasis-biology/>, <https://onco.cc/bottlenecks/b-brain-delivery/>, <https://onco.cc/bottlenecks/b-trial-design/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-adaura-8-year-os-jto-2026/>, <https://onco.cc/key-papers/paper-flaura-nejm-2018/>, <https://onco.cc/key-papers/paper-dillekas-cancer-med/> .