# OnCo record idea-bio2-functional-precision-rare (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-bio2-functional-precision-rare/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-bio2-functional-precision-rare" ;
  schema:name "Test drugs on the patient's own cancer cells when there is no trial to join"@en ;
  schema:description "For rare cancers there is often no genetic clue and no trial to join. Testing drugs directly on the patient's fresh tumour cells has guided treatment with reported benefit in a randomised haematology study and in paediatric case series; turnaround and tissue quality are the barriers."@en ;
  schema:url <https://onco.cc/ideas/idea-bio2-functional-precision-rare/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/j.ejca.2011.08.008> ;
  onco:cancers <https://onco.cc/cancers/sarcoma/>, <https://onco.cc/cancers/cholangiocarcinoma/> ;
  onco:technologies <https://onco.cc/technologies/functional-drug-testing/>, <https://onco.cc/technologies/organoids/>, <https://onco.cc/technologies/bh3-profiling/>, <https://onco.cc/technologies/pdx-models/> ;
  onco:companies <https://onco.cc/companies/curesponse/>, <https://onco.cc/companies/xilis/>, <https://onco.cc/companies/champions-oncology/>, <https://onco.cc/companies/sengine/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-rare-cancers/>, <https://onco.cc/bottlenecks/b-preclinical-models/>, <https://onco.cc/bottlenecks/b-biomarker-validation/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-gatta-eur-j-cancer/> .