# OnCo record idea-bio2-histotripsy-immune-priming (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-bio2-histotripsy-immune-priming/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-bio2-histotripsy-immune-priming" ;
  schema:name "Mechanically pulverise one tumour with ultrasound to wake the immune system"@en ;
  schema:description "Focused ultrasound can break a tumour apart without heat or cuts, leaving debris the immune system can learn from. Doing that to one tumour may help treat the rest."@en ;
  schema:url <https://onco.cc/ideas/idea-bio2-histotripsy-immune-priming/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1001/jamanetworkopen.2019.2535> ;
  onco:cancers <https://onco.cc/cancers/hcc/>, <https://onco.cc/cancers/colorectal/> ;
  onco:technologies <https://onco.cc/technologies/hifu-histotripsy/>, <https://onco.cc/technologies/thermal-ablation/>, <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/technologies/irreversible-electroporation/> ;
  onco:companies <https://onco.cc/companies/histosonics/> ;
  onco:terms <https://onco.cc/terms/abscopal-effect/>, <https://onco.cc/terms/immunogenic-cell-death/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-tme-immunosuppression/>, <https://onco.cc/bottlenecks/b-surgery-radiation-innovation/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-haslam-jama-netw-open/> .