# OnCo record idea-bio2-hypoxia-guided-adenosine (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-bio2-hypoxia-guided-adenosine/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-bio2-hypoxia-guided-adenosine" ;
  schema:name "Use a hypoxia scan to pick patients for adenosine-pathway drugs"@en ;
  schema:description "Tumours starved of oxygen produce a chemical that switches immune cells off. A scan can show which tumours are starved, and those are the ones to treat with blockers."@en ;
  schema:url <https://onco.cc/ideas/idea-bio2-hypoxia-guided-adenosine/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1001/jamanetworkopen.2019.2535> ;
  onco:cancers <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/prostate/> ;
  onco:technologies <https://onco.cc/technologies/pet/>, <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/technologies/rna-seq/> ;
  onco:pathways <https://onco.cc/pathways/hif-vhl/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-tme-immunosuppression/>, <https://onco.cc/bottlenecks/b-immunotherapy-response/>, <https://onco.cc/bottlenecks/b-biomarker-validation/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-haslam-jama-netw-open/> .