# OnCo record idea-bio2-mrd-triggered-neoantigen-vaccine (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-bio2-mrd-triggered-neoantigen-vaccine/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-bio2-mrd-triggered-neoantigen-vaccine" ;
  schema:name "Personalised vaccines given only when the blood test turns positive"@en ;
  schema:description "Individualised mRNA cancer vaccines take weeks to manufacture and work best against minimal residual disease. Making the vaccine at surgery and giving it only when a blood tumour DNA test turns positive matches both facts and concentrates the cost on the minority who will relapse."@en ;
  schema:url <https://onco.cc/ideas/idea-bio2-mrd-triggered-neoantigen-vaccine/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa2200075> ;
  onco:cancers <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/melanoma/> ;
  onco:technologies <https://onco.cc/technologies/neoantigen-mrna-vaccine/>, <https://onco.cc/technologies/mrd-testing/> ;
  onco:drugs <https://onco.cc/drugs/autogene-cevumeran/>, <https://onco.cc/drugs/intismeran-autogene/> ;
  onco:companies <https://onco.cc/companies/biontech/>, <https://onco.cc/companies/moderna/> ;
  onco:terms <https://onco.cc/terms/neoantigen/>, <https://onco.cc/terms/mrd/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-dormancy-mrd/>, <https://onco.cc/bottlenecks/b-drug-pricing/>, <https://onco.cc/bottlenecks/b-manufacturing-cell-therapy/> .