# OnCo record idea-bio2-sonobiopsy (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-bio2-sonobiopsy/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-bio2-sonobiopsy" ;
  schema:name "Ultrasound-assisted blood test instead of a brain biopsy"@en ;
  schema:description "Brain tumours release little DNA into blood because of the blood-brain barrier. Sonobiopsy briefly opens the barrier with focused ultrasound and microbubbles, raising circulating tumour DNA severalfold so a blood sample can replace repeat surgical biopsy for diagnosis and resistance monitoring in glioma and brain metastases."@en ;
  schema:url <https://onco.cc/ideas/idea-bio2-sonobiopsy/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://www.fusfoundation.org> ;
  onco:cancers <https://onco.cc/cancers/glioblastoma/> ;
  onco:technologies <https://onco.cc/technologies/bbb-focused-ultrasound/>, <https://onco.cc/technologies/liquid-biopsy/>, <https://onco.cc/technologies/mrd-testing/> ;
  onco:companies <https://onco.cc/companies/insightec/> ;
  onco:terms <https://onco.cc/terms/blood-brain-barrier/>, <https://onco.cc/terms/ctdna/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-brain-delivery/>, <https://onco.cc/bottlenecks/b-tumor-heterogeneity/> .