# OnCo record idea-bio2-vascular-normalisation-window (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-bio2-vascular-normalisation-window/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-bio2-vascular-normalisation-window" ;
  schema:name "Use imaging to find the window when tumour blood vessels are working properly"@en ;
  schema:description "Low doses of anti-blood-vessel drugs briefly make tumour vessels work better, which helps immune cells and other drugs get in. Scans can find that window for each patient."@en ;
  schema:url <https://onco.cc/ideas/idea-bio2-vascular-normalisation-window/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1001/jamanetworkopen.2019.2535> ;
  onco:related <https://onco.cc/pairings/io-plus-vegf/> ;
  onco:technologies <https://onco.cc/technologies/antiangiogenic/>, <https://onco.cc/technologies/mri/>, <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/technologies/pet/> ;
  onco:drugs <https://onco.cc/drugs/bevacizumab/>, <https://onco.cc/drugs/lenvatinib/> ;
  onco:pathways <https://onco.cc/pathways/vegf-angiogenesis/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-tme-immunosuppression/>, <https://onco.cc/bottlenecks/b-dose-optimisation/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-haslam-jama-netw-open/> .