# OnCo record idea-bladder-preservation-mibc (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-bladder-preservation-mibc/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-bladder-preservation-mibc" ;
  schema:name "Bladder preservation for MIBC after perioperative EV + pembrolizumab complete response"@en ;
  schema:description "If the ADC-immunotherapy combination erases the tumour in more than half of patients before surgery, some may not need their bladder removed at all."@en ;
  schema:url <https://onco.cc/ideas/idea-bladder-preservation-mibc/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03924895>, <https://clinicaltrials.gov/study/NCT04700124> ;
  onco:cancers <https://onco.cc/cancers/urothelial/> ;
  onco:technologies <https://onco.cc/technologies/mrd-testing/>, <https://onco.cc/technologies/mri/> ;
  onco:drugs <https://onco.cc/drugs/enfortumab-vedotin/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/signatera/> ;
  onco:trials <https://onco.cc/trials/ev-303/>, <https://onco.cc/trials/ev-304/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-pembrolizumab-urothelial-n-engl-j-med-2017/>, <https://onco.cc/key-papers/paper-pembrolizumab-urothelial-lancet-oncol-2017/>, <https://onco.cc/key-papers/paper-ev-302-nejm-2024/> .