# OnCo record idea-car-t-replaces-transplant (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-car-t-replaces-transplant/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-car-t-replaces-transplant" ;
  schema:name "One CAR-T infusion instead of autologous transplant"@en ;
  schema:description "Replace high-dose melphalan and stem-cell rescue with a single infusion of the patient's engineered T cells after induction."@en ;
  schema:url <https://onco.cc/ideas/idea-car-t-replaces-transplant/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT04923893>, <https://clinicaltrials.gov/study/NCT04181827> ;
  onco:cancers <https://onco.cc/cancers/multiple-myeloma/> ;
  onco:technologies <https://onco.cc/technologies/car-t/>, <https://onco.cc/technologies/autologous-stem-cell-transplant/> ;
  onco:drugs <https://onco.cc/drugs/ciltacabtagene-autoleucel/> ;
  onco:trials <https://onco.cc/trials/cartitude-5/>, <https://onco.cc/trials/cartitude-4/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-ciltacabtagene-autoleucel-multiple-myeloma-front-immunol-2022/>, <https://onco.cc/key-papers/paper-ciltacabtagene-autoleucel-multiple-myeloma-j-clin-oncol-2023/>, <https://onco.cc/key-papers/paper-ciltacabtagene-autoleucel-multiple-myeloma-clin-cancer-res-2024/> .