# OnCo record idea-cost-shorter-course-trials (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-cost-shorter-course-trials/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-cost-shorter-course-trials" ;
  schema:name "Fund trials that test shorter courses of the most expensive adjuvant drugs"@en ;
  schema:description "The PERSEPHONE trial showed six months of trastuzumab after surgery is as good as twelve, halving the drug cost; no company will run such trials, so public funders and charities must."@en ;
  schema:url <https://onco.cc/ideas/idea-cost-shorter-course-trials/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/S0140-6736(19)30650-6> ;
  onco:cancers <https://onco.cc/cancers/breast-her2-positive/>, <https://onco.cc/cancers/breast-hr-positive/> ;
  onco:drugs <https://onco.cc/drugs/trastuzumab/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/abemaciclib/>, <https://onco.cc/drugs/olaparib/> ;
  onco:institutions <https://onco.cc/institutions/nci/>, <https://onco.cc/institutions/cruk/> ;
  onco:trials <https://onco.cc/trials/persephone/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-dose-optimisation/>, <https://onco.cc/bottlenecks/b-drug-pricing/>, <https://onco.cc/bottlenecks/b-trial-design/>, <https://onco.cc/bottlenecks/b-incentive-misalignment/> .