# OnCo record idea-crc-screening-uptake-and-age-extension (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-crc-screening-uptake-and-age-extension/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-crc-screening-uptake-and-age-extension" ;
  schema:name "Treat screening uptake, not test sensitivity, as the thing to optimise, and settle the age extension with a trial rather than a model"@en ;
  schema:description "The only randomised trial of screening colonoscopy cut bowel cancer by 18 percent because only 42 percent of the people invited turned up. A test that is 20 percent more sensitive but is taken by the same people buys far less than an invitation that 20 percent more people accept."@en ;
  schema:url <https://onco.cc/ideas/idea-crc-screening-uptake-and-age-extension/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://europepmc.org/article/MED/36214590>, <https://europepmc.org/article/MED/20463339>, <https://clinicaltrials.gov/study/NCT00883792> ;
  onco:tag "colorectal-evidence" ;
  onco:related <https://onco.cc/roadmaps/colorectal-roadmap/>, <https://onco.cc/roadmaps/early-detection-roadmap/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/early-onset-colorectal/> ;
  onco:sections <https://onco.cc/fronts/early-detection/>, <https://onco.cc/fronts/prevention/> ;
  onco:technologies <https://onco.cc/technologies/colorectal-screening/>, <https://onco.cc/terms/colonoscopy/>, <https://onco.cc/drugs/cologuard/>, <https://onco.cc/technologies/liquid-biopsy/>, <https://onco.cc/technologies/ai-endoscopy-detection/> ;
  onco:terms <https://onco.cc/terms/fit-test/> ;
  onco:trials <https://onco.cc/trials/nordicc/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-early-detection/>, <https://onco.cc/bottlenecks/b-prevention-adoption/>, <https://onco.cc/bottlenecks/b-global-access/>, <https://onco.cc/bottlenecks/b-workforce/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-bretthauer-nordicc-colonoscopy-screening-nejm-2022/>, <https://onco.cc/key-papers/paper-hardcastle-nottingham-faecal-occult-blood-lancet-1996/>, <https://onco.cc/key-papers/paper-kaminski-adenoma-detection-rate-interval-cancer-nejm-2010/>, <https://onco.cc/key-papers/paper-imperiale-multitarget-stool-dna-screening-nejm-2014/>, <https://onco.cc/key-papers/paper-siegel-colorectal-cancer-statistics-ca-2023/> .
