# OnCo record idea-ctdna-guided-dlbcl-frontline (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-ctdna-guided-dlbcl-frontline/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-ctdna-guided-dlbcl-frontline" ;
  schema:name "ctDNA-guided escalation and de-escalation in frontline DLBCL"@en ;
  schema:description "Use an ultra-sensitive blood test after two cycles to decide who needs more than R-CHOP and who can stop early."@en ;
  schema:url <https://onco.cc/ideas/idea-ctdna-guided-dlbcl-frontline/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO.2018.78.5246> ;
  onco:cancers <https://onco.cc/cancers/dlbcl/> ;
  onco:technologies <https://onco.cc/technologies/ctdna-lymphoma-monitoring/> ;
  onco:drugs <https://onco.cc/drugs/epcoritamab/>, <https://onco.cc/drugs/polatuzumab-vedotin/> ;
  onco:terms <https://onco.cc/terms/mrd/> ;
  onco:trials <https://onco.cc/trials/epcore-dlbcl-1/>, <https://onco.cc/trials/epcore-dlbcl-2/>, <https://onco.cc/trials/epcore-nhl-1/>, <https://onco.cc/trials/nct06508658/>, <https://onco.cc/trials/nct07226752/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-kurtz-j-clin-oncol/>, <https://onco.cc/key-papers/paper-epcoritamab-dlbcl-drugs-2023/>, <https://onco.cc/key-papers/paper-epcoritamab-dlbcl-blood-2025/> .