# OnCo record idea-ctdna-guided-parp-duration (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-ctdna-guided-parp-duration/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-ctdna-guided-parp-duration" ;
  schema:name "ctDNA-guided duration of PARP maintenance"@en ;
  schema:description "Stop PARP inhibitors early in women whose blood shows no residual tumour DNA, and extend or switch in those whose ctDNA persists or reverts BRCA."@en ;
  schema:url <https://onco.cc/ideas/idea-ctdna-guided-parp-duration/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT01844986>, <https://clinicaltrials.gov/study/NCT02655016> ;
  onco:cancers <https://onco.cc/cancers/ovarian/> ;
  onco:technologies <https://onco.cc/technologies/mrd-testing/>, <https://onco.cc/technologies/parp-inhibitor/> ;
  onco:drugs <https://onco.cc/drugs/olaparib/>, <https://onco.cc/drugs/niraparib/> ;
  onco:terms <https://onco.cc/terms/mrd/> ;
  onco:trials <https://onco.cc/trials/solo-1/>, <https://onco.cc/trials/prima/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-solo-1-nejm-2018/>, <https://onco.cc/key-papers/paper-niraparib-ovarian-n-engl-j-med-2016/>, <https://onco.cc/key-papers/paper-prima-niraparib-nejm-2019/> .