# OnCo record idea-data-in-silico-trials-calibrated (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-data-in-silico-trials-calibrated/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-data-in-silico-trials-calibrated" ;
  schema:name "In silico trials to prioritise combinations, scored against later real trials"@en ;
  schema:description "Simulate trials of drug combinations in populations of virtual patients to decide which real trials to run, and keep score of how often the simulations were right."@en ;
  schema:url <https://onco.cc/ideas/idea-data-in-silico-trials-calibrated/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41591-021-01312-x> ;
  onco:related <https://onco.cc/ideas/idea-data-digital-twin-predict-then-observe/>, <https://onco.cc/ideas/idea-data-open-cell-foundation-model/> ;
  onco:sections <https://onco.cc/fronts/ai-computation/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-ai-validation/>, <https://onco.cc/bottlenecks/b-combination-space/>, <https://onco.cc/bottlenecks/b-trial-design/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-wu-nat-med/> .