# OnCo record idea-dtc-colonisation-determinants (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-dtc-colonisation-determinants/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-dtc-colonisation-determinants" ;
  schema:name "What decides which disseminated cells ever colonise?"@en ;
  schema:description "Most cancer cells that spread die or sleep forever; a few grow into lethal metastases. Nobody can yet tell them apart, and doing so would show whom to treat after surgery."@en ;
  schema:url <https://onco.cc/ideas/idea-dtc-colonisation-determinants/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/nature17038> ;
  onco:tag "mechanism", "open-question" ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/prostate/> ;
  onco:technologies <https://onco.cc/technologies/mrd-testing/>, <https://onco.cc/technologies/single-cell-spatial/> ;
  onco:institutions <https://onco.cc/institutions/mount-sinai/>, <https://onco.cc/institutions/mskcc/>, <https://onco.cc/institutions/cold-spring-harbor/> ;
  onco:pathways <https://onco.cc/pathways/metastatic-cascade/>, <https://onco.cc/pathways/tumor-dormancy/> ;
  onco:terms <https://onco.cc/terms/disseminated-tumor-cells/>, <https://onco.cc/terms/late-recurrence/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-massague-nature/> .