# OnCo record idea-field-interception (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-field-interception/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-field-interception" ;
  schema:name "Intercept cancer at the field stage"@en ;
  schema:description "Whole regions of tissue carry cancer mutations long before a tumour exists. Detecting and treating the field, not the tumour, could prevent cancers rather than cure them."@en ;
  schema:url <https://onco.cc/ideas/idea-field-interception/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1126/science.aaa6806> ;
  onco:tag "mechanism", "open-question" ;
  onco:cancers <https://onco.cc/cancers/esophageal/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/head-and-neck/> ;
  onco:technologies <https://onco.cc/technologies/precancer-ablation/>, <https://onco.cc/technologies/chemoprevention/>, <https://onco.cc/technologies/endoscopic-resection/> ;
  onco:targets <https://onco.cc/targets/tp53/> ;
  onco:institutions <https://onco.cc/institutions/cruk/>, <https://onco.cc/institutions/francis-crick/> ;
  onco:pathways <https://onco.cc/pathways/field-cancerisation/>, <https://onco.cc/pathways/clonal-evolution/> ;
  onco:terms <https://onco.cc/terms/barretts-esophagus/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-vogelstein-surfing-p53-network-nature-2000/> .