# OnCo record idea-fus-plus-adc-glioma (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-fus-plus-adc-glioma/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-fus-plus-adc-glioma" ;
  schema:name "Focused-ultrasound BBB opening to deliver ADCs and radioligands to glioma"@en ;
  schema:description "Brain tumours have targets that ADCs could hit, but antibodies cannot cross the barrier. Open the barrier with ultrasound first."@en ;
  schema:url <https://onco.cc/ideas/idea-fus-plus-adc-glioma/> ;
  schema:dateModified "2026-09-06"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/S1470-2045(23)00112-2> ;
  onco:cancers <https://onco.cc/cancers/glioblastoma/> ;
  onco:technologies <https://onco.cc/technologies/bbb-focused-ultrasound/>, <https://onco.cc/technologies/adc/>, <https://onco.cc/technologies/radioimmunotherapy/> ;
  onco:targets <https://onco.cc/targets/egfr/>, <https://onco.cc/targets/b7h3/> ;
  onco:terms <https://onco.cc/terms/blood-brain-barrier/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-sonabend-lancet-oncol/>, <https://onco.cc/key-papers/paper-egfr-glioblastoma-mol-oncol-2018/>, <https://onco.cc/key-papers/paper-egfr-glioblastoma-sci-signal-2009/>, <https://onco.cc/key-papers/paper-b7-h3-glioblastoma-int-j-biol-sci-2023/> .