# OnCo record idea-gbc-ctdna-residual-disease-guided-adjuvant-trial (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-gbc-ctdna-residual-disease-guided-adjuvant-trial/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-gbc-ctdna-residual-disease-guided-adjuvant-trial" ;
  schema:name "A ctDNA residual disease-guided adjuvant trial after gallbladder cancer resection"@en ;
  schema:description "After surgery for bile duct or gallbladder cancer, a blood test for leftover tumour DNA picks out the people whose cancer will return with hazard ratios of 16 to 26 in two recent cohorts. Nobody has yet tested giving those people more than the standard capecitabine."@en ;
  schema:url <https://onco.cc/ideas/idea-gbc-ctdna-residual-disease-guided-adjuvant-trial/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://europepmc.org/article/MED/42583118>, <https://europepmc.org/article/MED/39772829> ;
  onco:tag "gallbladder-evidence" ;
  onco:related <https://onco.cc/roadmaps/ctdna-tests/>, <https://onco.cc/ideas/idea-btc-ctdna-fgfr-resistance/> ;
  onco:cancers <https://onco.cc/cancers/gallbladder/>, <https://onco.cc/cancers/biliary-tract-cancer/> ;
  onco:technologies <https://onco.cc/technologies/liquid-biopsy/>, <https://onco.cc/technologies/mrd-testing/> ;
  onco:drugs <https://onco.cc/drugs/signatera/>, <https://onco.cc/drugs/capecitabine/>, <https://onco.cc/drugs/gemcitabine-cisplatin/>, <https://onco.cc/drugs/durvalumab/> ;
  onco:terms <https://onco.cc/terms/ctdna/>, <https://onco.cc/terms/mrd/>, <https://onco.cc/terms/neoadjuvant-adjuvant/>, <https://onco.cc/terms/de-escalation/> ;
  onco:trials <https://onco.cc/trials/bilcap/>, <https://onco.cc/trials/acticca-1/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-dormancy-mrd/>, <https://onco.cc/bottlenecks/b-trial-design/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-malla-ctdna-resected-biliary-tract-cancer-esmo-gi-onc-2026/>, <https://onco.cc/key-papers/paper-yu-ctdna-early-recurrence-biliary-tract-cancer-jco-po-2025/> .