# OnCo record idea-hcc-io-before-transplant (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-hcc-io-before-transplant/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-hcc-io-before-transplant" ;
  schema:name "Immunotherapy downstaging to transplant with a safe washout"@en ;
  schema:description "Use immunotherapy to shrink liver cancer enough for a transplant, and find the safe gap between the last dose and surgery so the new liver is not rejected."@en ;
  schema:url <https://onco.cc/ideas/idea-hcc-io-before-transplant/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://doi.org/10.1111/ajt.16448> ;
  onco:cancers <https://onco.cc/cancers/hcc/> ;
  onco:technologies <https://onco.cc/technologies/liver-transplant-oncology/>, <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:drugs <https://onco.cc/drugs/nivolumab/>, <https://onco.cc/drugs/atezolizumab/> ;
  onco:trials <https://onco.cc/trials/checkmate-9dw/>, <https://onco.cc/trials/imbrave050/>, <https://onco.cc/trials/imbrave150/>, <https://onco.cc/trials/nct03755791/>, <https://onco.cc/trials/nct05904886/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-tabrizian-am-j-transplant/>, <https://onco.cc/key-papers/paper-imbrave150-nejm-2020/>, <https://onco.cc/key-papers/paper-atezolizumab-hcc-j-hepatol-2022/>, <https://onco.cc/key-papers/paper-nivolumab-hcc-jama-oncol-2020/> .