# OnCo record idea-her2-adc-serous-endometrial (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-her2-adc-serous-endometrial/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-her2-adc-serous-endometrial" ;
  schema:name "HER2 ADCs as standard for HER2-positive serous endometrial cancer"@en ;
  schema:description "Serous endometrial cancers often overproduce HER2. Enhertu already works in them; testing HER2 in every p53-abnormal tumour and using the ADC earlier could change outcomes for the worst subtype."@en ;
  schema:url <https://onco.cc/ideas/idea-her2-adc-serous-endometrial/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT04482309> ;
  onco:cancers <https://onco.cc/cancers/endometrial/> ;
  onco:targets <https://onco.cc/targets/her2/>, <https://onco.cc/targets/tp53/> ;
  onco:drugs <https://onco.cc/drugs/trastuzumab-deruxtecan/>, <https://onco.cc/drugs/trastuzumab/> ;
  onco:terms <https://onco.cc/terms/endometrial-molecular-classes/> ;
  onco:trials <https://onco.cc/trials/destiny-pantumor02/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-yarden-sliwkowski-erbb-network-nrmcb-2001/> .